I was always wondering if there could be a small Linux partition for additional information of NTFS partitions, like meta data stored as a separate file (or database). And off course it would need some virtualization layer like WINE does for the file path mapping. Then it would be possible to use NTFS as system drive and for games.
Obviously this would be problematic and performance wouldn't be great either (assuming), and it would complicate things for end user and developers too. But I was always thinking if this would be possible.