My own experience with RSD is why I have a rule with friends, since many of them experience it too.
If I have said I can't talk to them for a bit - be it an extended isolation time, or even if I AM that angry with them - there is an exception in place for them to periodically check if we are still friends. If I'm not angry enough to end the friendship, then I'm not too angry to accommodate RSD, no matter what happened.