Bah, I typoed. I'm running 250 first layer/240 following layers, which is still lower than what most usually recommend. I was running 235 pretty consistently previously. I'll have to try printing a temp tower with the bigger nozzle. Here's one from the 0.4mm nozzle, granted also with my prior Rapido 1 (RIP).
Above 245 or so, I started getting a lot of very fine/wispy stringing. It basically looked like ultrafine thread and would get itself stuck in my hot end fans.
You will then also need more part cooling fan as there is more plastic bulk to be cooling.
Thanks to somewhat low chamber temps (350mm^3 printer with only acrylic panels), I've been keeping cooling somewhat low. I recently added some more bed fans to help my bed filter out, so maybe I can try a bit more if it starts becoming an issue.