I dropped my handset a bunch of times - came out second in a fight once and wrecked some nerves in my hand - but it survived every time.
It's when we were abroad and trying to rent those funny little scooters that I dropped it on cobblestones and it was insta-dead. And me having already done arrive-can with my info stored on my phone that's now unusable. Wheeee.
I don't think even an otterbox would have saved it, though. The universe has a sense of humour and it's a very dark one.