I spent a few months last year running Nobara. I'm back on Windows unfortunately. There are a ton of games that ran just fine, but there's also a lot of little issues. For example, in Grim Dawn I couldn't type in chat, in Pathfinder WotR I simply couldn't get mods to work, STALKER Anomaly simply wouldn't load. Then there was the big issue of my mouse cursor dropping below full screen games. Still there, but not visible. The only fix I could use was to restart the computer.
It's tantalizingly close to ready, and if you don't care about modding it probably already is. For me it just didn't work out, yet.