I'm happy to report Straterra leaves me personally totally intact. I get a little more bored on the weekends but otherwise feel fine. I only drink socially but so far Alcohol presents no issues. I'm a full-time stoner and I haven't noticed any differences in my Cannabis effects. I do smoke just a little less because I'm a little more focused during the day but it's not a big difference.
I got off stimulants 20 years ago because I hated feeling like I was 'either on or off' and Straterra has given me a steady middle ground that's supremely pleasant. I was very against meds but after I hit 40 and was working from home over pandemic my symptoms just weren't manageable any more and Straterra helped immensely.