With unique passwords, the attack surface just changes. Instead of attacking the passwords, attackers attack the password managers. LastPass, Okta, and Passwordstate each had breaches, and the first two are quite popular.
That doesn't mean Bitwarden is at risk (not sure if it has been targeted), it just means that attackers are finding success going after password managers, so they could go after Bitwarden. Maybe they'll sneak in an xz-style bug that'll allow attackers to steal credentials en-route, idk.
So it's a matter of good/better/best:
good - use a password manager to prevent password leaks from providing access to other accounts
better - use 2FA to prevent "password recovery" attacks; these are often targeted in nature, so there's a lot less risk here
best - use a separate 2FA from your password manager to prevent a breach from exposing all of your accounts
The overhead from using a separate 2FA app is pretty low, just make sure it encrypts your keys and you trust it (FOSS is a good indicator of trust).