Seems that way. Windows 10 support stops October 2025. You have until then to switch, but I suggest getting familiar with a Linux distro now if you can.
It is a matter if physics. Humans have to much mass. You might successfully freeze the outside but the organs will be destroyed by ice crystals. There also is the issue of if we should but that is a discussion to another day.
The most obvious way around that would be some kind of cryoprotectant, but those have all proven very toxic so far. The next frontier would be trihalose, which we've figured out how to produce in quantity recently, so watch out for news on that. To get something hot evenly and quickly, RF heating works great, but it's not obvious there's any equivalent for cooling, unless you're dealing with a few already-cryogenic atoms. One thing I've wondered about is using high pressures that depress the freezing point of water, but those kinds of pressures are sometimes biochemically toxic on their own. No research on short exposure in animals seems to exists, unfortunately.
It's so close to working, I feel like we'll solve it eventually, but I don't know when or how.
If I remember correctly the issue has to do with the water in your bodies you can only cool water so fast. If I am recalling correctly you couldn't even do it with absolute zero temperatures as the water takes to much time to lose energy.
Well, no. Reductionism still holds. If you could magically make the water everywhere inside super cold, it would behave locally just like water in a smaller creature. Unfortunately, it seems impossible to do that. Even pumping coolant through the circulatory system, which is a thing I know at least happens in some related procedures.
For context on the size of the brain sample and the data collected from it, we need to get into mind-numbingly colossal numbers. The cubic millimeter of brain matter is only one-millionth of the size of an adult human brain, and yet the imaging scans and full map of its intricacies comprises 1.4 petabytes, or 1.4 million gigabytes. If someone were to utilize the Google/Harvard approach to mapping an entire human brain today, the scans would fill up 1.6 zettabytes of storage.
Taking these logistics further, storing 1.6 zettabytes on the cheapest consumer hard drives (assuming $0.03 per GB) would cost a cool $48 billion, and that's without any redundancy. The $48 billion price tag does not factor in the cost of server hardware to put the drives in, networking, cooling, power, and a roof to put over this prospective data center. The roof in question will also have to be massive; assuming full server racks holding 1.8 PB, the array of racks needed to store the full imaging of a human brain would cover over 140 acres if smushed together as tightly as possible. This footprint alone, without any infrastructure, would make Google the owner of one of the top 10 largest data centers in the world...
One minor detail that the brain is not homogenous. I don't know where the sample came from, but you'd probably get different results from grey vs white matter, or the cerebellum vs cerebrum, etc.
Still going to be a gargantuan amount of data though, no matter how you slice it.
This is also pretty lightly compressed, though. If you're trying to do mind uploads you can probably shave off orders of magnitude pretty easily, since in silico neurons don't need any of the functional structures as long as they act the same way.
I'm interested to see how this develops. If this is a base model other companies can freely acquire with no license costs or restrictions, then it might quickly expand the range of humanoid robots available.
I'm expecting China to take the lead in manufacturing "cheap" humanoid robots, and exporting them. There are demos of humanoid robots training themselves to do simple household tasks. How soon before you can buy a Humanoid Robot Maid in the shops?
If this is a base model other companies can freely acquire with no license costs or restrictions, then it might quickly expand the range of humanoid robots available.
Let's hope the license forces the return of any advancements and improvements back to the project, and not keep it for themselves as proprietary.
Great achievement. Not much on the tech though. According to the ucam press release, they used an AAV1 viral delivery system. Given that the therapy is permanent, I would expect integration of the therapeutic gene into the patient's genome (in the targeted tissue). Anyone have more on this?
I don't know anything about the treatment. But to be hereditary the genome changes would have to affect gametes. If genes are only changed in other targeted tissue then the changes wouldn't be inherited.
No
The gene therapy is applied locally. They operate on the ear to enable access to the relevant tissue and then apply the therapy. So it should only affect cells in the ear.
Additionally, it is unclear to me whether the therapeutic gene is integrated into the genome. It might not be.
For transmission to offspring, you would need to edit germ line cells (sex cells) and you would need to integrate the gene into the genome.
After visiting there in 2010, right before they got the FIFA World Cup, they were well on their way toward a stable infrastructure. Then, after they got the World Cup, they switched from country-wide stable infrastructure to major construction projects for the like 2-weeks the event took place. It was sad to see those living in little shanty towns, with makeshift power and cable setups, and know that a better way was coming before soccer/football ruined it.
Really glad to see the country taking a win and helping out their country, even if it s likely not explicitly their goal.
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